WebJun 11, 2024 · “The ALPINE trial is the only head-to-head study in CLL to demonstrate an efficacy advantage for a more selective BTK inhibitor over ibrutinib. Compared to ibrutinib, BRUKINSA demonstrated... WebOct 19, 2024 · Corrado Tamburino, MD, PhD. Results of the SCOPE II trial indicate ACURATE neo valves failed to demonstrate non-inferiority when compared head-to-head against CoreValve Evolut valves in a randomized clinical trial. The study, which was presented at Transcatheter Cardiovascular Therapies (TCT) Connect 2024, examined …
Head-to-Head Clinical Trial Comparisons Cytel
WebSep 28, 2024 · A head-to-head comparison of the efficacy and safety of ixekizumab and adalimumab in biological-naïve patients with active psoriatic arthritis: 24-week results of a randomised, open-label,... WebDec 1, 2016 · Depending on the trial hypothesis, head-to-head studies may be designed as a superiority, equivalence or non-inferiority trial. The aim of a superiority trial design is to demonstrate that one intervention is superior to another, with a sample size based on a pre-specified minimum clinically important difference. tan healthcare orange texas
Head-to-head trials in inflammatory bowel disease: past ... - Nature
WebMay 26, 2024 · Nowadays, data from larger head-to-head trials comparing DOACs with LMWH in cancer-associated VTE are available. The SELECT-D trial for rivaroxaban, the HOKUSAI VTE-Cancer trial for edoxaban, and the CARAVAGGIO trial for apixaban are briefly described below (Khorana et al., 2024; Raskob et al., 2024; Young et al., … WebDOI: 10.1016/j.eururo.2024.03.001 Corpus ID: 258030871; Head-to-head Comparison of the Diagnostic Accuracy of Prostate-specific Membrane Antigen Positron Emission Tomography and Conventional Imaging Modalities for Initial Staging of Intermediate- to High-risk Prostate Cancer: A Systematic Review and Meta-analysis. WebSep 22, 2016 · There are several reasons for performing head-to-head trials. The health authorities may request an active comparator when considering the reimbursement of … tan heap ho