Hif ihc
WebGene summary (Entrez)i. Useful information about the gene from Entrez. This gene encodes the alpha subunit of transcription factor hypoxia-inducible factor-1 (HIF-1), which is a … WebHypoxia inhibits degradation of the α subunit, which leads to its stabilization (1,2). HIF, in turn, regulates the transcription of a variety of genes that respond to hypoxia conditions (1,2). There are several isoforms of the HIF α subunit (2). Studies have found that HIF-1α and HIF-2α expression is increased in some human cancers (2).
Hif ihc
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Web9 de dez. de 2024 · HIF-targeting therapies that are currently under development may be considered to overcome treatment resistance or to slow metastatic proliferation in the ... (Indica Lab) Multiplex IHC module. Web24 de nov. de 2024 · Then, we will dissect the underlying mechanisms in VHL/HIF axis-driven PPGL pathogenesis, with special attention paid to the interplay between the VHL/HIF axis and cancer cell metabolism. Finally, we will summarize the currently available compounds/drugs targeting this axis which could be potentially used as PPGLs …
WebBackground: Hypoxia inducible factor 1α (HIF-1α) is a protein related with carcinogenesis and metastasis in many tumors. However, little is known about the prognostic value of … WebDetails: HIF-1 alpha antibody (clone ESEE122) was used for IHC-P analysis of tissue sections from human subjects with advanced esophageal …
WebHIF-1 alpha IHC Antibody . Ready To Use . Catalog Number: Size: Price: Availability: IW-PA1041: 9 ml: $258: Yes: Description: HIF-1α (Hypoxia-inducible factor 1α,HIF1A) is a … WebA specific band was detected for HIF-1 alpha/HIF1A at approximately 116 kDa (as indicated) using 10 µg/mL of Mouse Anti-Human/Mouse/Rat HIF-1 alpha/HIF1A Monoclonal Antibody (Catalog # MAB1536). This experiment was conducted under reducing conditions and using the 12-230 kDa separation system. Knockout Validated View Larger.
WebFigure 1. HIF-1a staining of HeLa cells. Anti-HIF-1a antibody [EPR16897] (ab179483) was used at 1/50 dilution with goat anti-rabbit IgG (Alexa Fluor ® 488) secondary antibody. Cells were treated with 0.6 nM CoCl 2 for 6 hours. Application. Recommended product. Western blot, immunocytochemistry. Anti-HIF-1a antibody (ab179483) ELISA.
Web11 de dez. de 2024 · Essential features. Carbonic anhydrase IX (CAIX / CA9) is a transmembrane protein (membranous expression) ( Am J Clin Pathol 2014;141:219 ) Primarily used in differentiating kidney tumors but not specific to renal primary tumors. Diffusely positive in clear cell renal cell carcinoma (box-like) and clear cell papillary renal … how are puts pricedWeb15 de set. de 2024 · Abstract. Purpose: Clear cell renal cell carcinoma (ccRCC) is frequently associated with inactivation of the von Hippel-Lindau tumor suppressor, resulting in activation of HIF-1α and HIF-2α. The current paradigm, established using mechanistic cell-based studies, supports a tumor promoting role for HIF-2α, and a tumor suppressor role … how many miles from maryland to floridaWebHá 1 dia · Happy easter from the IHF. In the spirit of Easter, IHF President Dr Hassan Moustafa, on behalf of the International Handball Federation, would like to extend his … how are putins daughters being sanctionedWebHIF-1alpha/HIF1A Mouse Monoclonal Antibody -20ºC保存，需避免反复冻融。 Western一抗稀释液-20℃或4℃保存，一年有效，Western一抗稀释液优先推荐4℃保存，长期不使用 … how are push pops madeWebIHC image of HIF-1-alpha staining in human normal colon formalin fixed paraffin embedded tissue section*, performed on a Leica Bond™ system using the standard protocol F. The … how are putters balancedWebSummary. HIF1 alpha antibody recognizes HIF1 alpha (HIF1a) protein, which is a subunit of the heterodimeric transcription factor hypoxia-inducible factor-1 (HIF-1). HIF-1 is a … how many miles from maine to californiaWeb29 de fev. de 2004 · Hypoxia-inducible factor (HIF-1) is an oxygen-dependent transcriptional activator, which plays crucial roles in the angiogenesis of tumors and mammalian … how are putters designed to fly