Human-gut phages harbor sporulation genes

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August undefined, 2024

Web9 sep. 2024 · Genes in this sporulation signature include characterised sporulation-associated genes, characterised genes not previously associated with sporulation and uncharacterised genes that have subsequently been demonstrated to be sporulation-associated30. Interestingly, the largest human gut-associated bacterial families … Web2 feb. 2024 · Clostridioides difficile, a nosocomial pathogen, is an emerging gut pathobiont causing antibiotic-associated diarrhea. C. difficile infection involves gut colonization and disruption of the gut epithelial barrier, leading to the induction of inflammatory/immune responses. The expression of two major exotoxins, TcdA and TcdB is the major cause of …

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WebBy mining genomes and gut-derived metagenomes, we identified sporulation genes that are preferentially encoded by phages that infect spore-forming bacteria. These included genes involved in chromosome partitioning, DNA damage repair, and cell wall … WebHuman-gut phages harbor sporulation genes 25 days ago By Daniel Schwartz , Josué A. Rodríguez-Ramos , Michael Shaffer , Rory Flynn bioRxiv Thank you for your interest in spreading the word about bioRxiv. NOTE: Your email address is requested solely to identify you as the sender of this article. engine cranks slowly after new timing chain

GitHub - jrr-microbio/sporulation_project: Collaboration project …

Web21 mrt. 2024 · Recent observations, combining observational and omics-based studies, have suggested that microbes inhabiting the human gut and the genes they carry, which make up the expansive and highly diverse human gut microbiome, can have a significant role in gut metabolism and health [].Within this large assembly of gut bacteria, archaea, … Web18 feb. 2024 · Phages from these 171 VCs mainly infect Escherichia, Enterobacter, Staphylococcus, and Klebsiella genera, reflecting the bias of the RefSeq database toward well-known clinically important and traditionally cultured bacteria. Web16 feb. 2024 · Identification of crAss-like phages in human gut metagenomes and viromes. In order to obtain a set of complete virus genomes, we extracted all circular contigs (with exact identical regions 50 ... engine crash bandicoot

Unique relationships between phages and endospore-forming …

Bacteriophages and their potential for treatment of ... - Nature

WebSome phages can only reproduce via a lytic lifecycle, in which they burst and kill their host cells. Other phages can alternate between a lytic lifecycle and a lysogenic lifecycle, in … WebHere, we introduce the Gut Phage Database, a collection of ∼142,000 non-redundant viral genomes (>10 kb) obtained by mining a dataset of 28,060 globally distributed human … dreamcast good gamesWebAnalysis of phage genomes identified in whole-community human gut metagenomes resulted in the delineation of at least three new candidate families of Caudovirales and … dreamcast green goblin

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Human-gut phages harbor sporulation genes

Massive expansion of human gut bacteriophage diversity

Web10 apr. 2024 · Download Citation Geochemical constraints on bacteriophage infectivity in terrestrial environments Lytic phages can be potent and selective inhibitors of microbial growth and can have profound ... WebSpore formation also modifies interactions among microorganisms such as infection by phages. Recent studies suggest that phages may counter dormancy-mediated defense …

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Web7 dec. 2024 · Bacillus subtilis as the Gram-positive model bacterium has been widely used in synthetic biology and biotechnology while the regulatory RNA tools for B. subtilis are still not fully explored. Here, a bottom-up approach is proposed for designing artificial trans-acting sRNAs. By engineering the intrinsic sRNA SR6, a minimized core scaffold … Web10 mrt. 2024 · However, metagenomic studies that focus on the RNA phages in the human gut are relatively few (Zhang et al., 2006; Manrique et al., 2024). Additional studies on the human gut virome have revealed that diverse genotypes of phages stably reside and play a distinct role in maintaining the host health (Minot et al., 2012; Abeles and Pride, 2014).

Web9 okt. 2014 · Temperate phages infect bacteria by injecting their DNA into bacterial cells, where it becomes incorporated into the host genome as a prophage. In the genome of Bacillus subtilis 168, an active prophage, SPβ, is inserted into a polysaccharide synthesis gene, spsM. Here, we show that a rearrangement … WebIn a typical cloning experiment, researchers first insert a piece of DNA, such as a gene, into a circular piece of DNA called a plasmid. This step uses restriction enzymes and DNA …

WebA bacteriophage, or phage for short, is a virus that infects bacteria. Like other types of viruses, bacteriophages vary a lot in their shape and genetic material. Phage genomes can consist of either DNA or RNA, and can contain as few as four genes or as many as several hundred ^ {1,2,3} 1,2,3 .

Web13 feb. 2014 · Phages have an important role in the gut ecosystem as evidenced by the diversity of phages in swine fecal viromes (Allen et al., 2011), phage ubiquity across more than 100 human fecal metagenomes ...

WebHuman-gut phages harbor sporulation genes. biorxiv.org. r/BiologyPreprints • Gas6 ameliorates intestinal mucosal immunosenescence to prevent the translocation of a gut pathobiont, Klebsiella pneumoniae, to the liver. biorxiv.org. engine crash bars for 2013 ninja 1000Web7 mei 2024 · Phages are the main source of within-species bacterial diversity and drivers of horizontal gene transfer. Prophage cargo can determine ecological interactions of a bacterium with other community members, and even its pathogenic potential, but we know little about the mechanisms that drive genetic diversity of these mobile genetic elements … dreamcast groupWebHuman-gut phages harbor sporulation genes. Endosporulation, a complex and ancient form of dormancy found among the Bacillota that involves hundreds of genes, is … dreamcast goldWeb126 Phage-encoded sporulation genes occur in diverse environments — The recovery of phage-127 encoded sporulation genes is not restricted to the human gut. We … engine.createstore storages pluginsWeb13 apr. 2024 · We believe that understanding phage-mediated gene transfer is crucial in interpreting complex ecological interactions within the human gut microbiome and is therefore worthy of further investigation. Authors’ Contributions. Conceptualization: A.N.S. and T.B.; Writing—original draft: T.B.; Writing—revision and editing: T.B., dreamcast grandiaWebHere we review in detail the known mechanisms of phage-mediated HGT, namely specialized and generalized transduction, lateral transduction, gene-transfer agents, and … engine crash barsWeb30 jul. 2024 · 细胞生物学教学课件-分子细胞生物学5版.pdf,1 LIFE BEGINS WITH CELLS A single ~200 micrometer (m) cell, the human egg, with sperm, which are also single cells. From the union of an egg and sperm will arise the 10 trillion cells of a human body. [Photo Researchers, Inc.] ike ourselves, the indi engine creek farm store