We compared the similarity and composition of the 1% most predominant clonotypes (1%_MPC) detected by each method. The Morisita–Horn (MH) similarity index was calculated for each replicate across all the methods for both TRA (Fig. 3a, left) and TRB (Fig. 3a, right) sequences. TRA repertoires from RACE-3 and … See more We set out to compare nine different academic or commercial protocols for library preparation and sequencing (Supplementary Methods and … See more For each method, we first analyzed the proportion of reads that were identified as TCRs (Fig. 1a and Supplementary Fig. 2). For seven of nine methods, we observed … See more To determine the accuracy of the different library amplifications for different clonotype frequencies, we compared the observed frequencies of the TCR from … See more One major limitation when analyzing TCR repertoire is the number of T cells that can be analyzed. Focusing on four RNA-based methods, we analyzed the … See more WebThe Morisita-Horn index is a popular angular overlap measure used both in ecological and immunological literature. It quantifies overlap as cosine of an angle between two standardized population vectors. It ranges between zero (no overlap) and one (perfect overlap). MH tends to be over-sensitive to abundant species. For details see Rempala and …
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WebMar 16, 2024 · The Morisita–Horn index is a measure of dispersion, which can be used to determine similarity between samples (for example, TCR repertoires). Unlike the Jaccard index, the Morisita–Horn index ... WebWe used a binomial mixed model with a Bayesian framework to compare the effect of host composition on the feeding patterns of Culicoides spp. and employed the Morisita-Horn Index to investigate the similarity of host use between farms for Culicoides stellifer and Culicoides insignis. sandy rogers facebook
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WebFeb 27, 2024 · The Morisita-Horn index, in contrast, has been found generally to perform well; it is less sensitive than other quantitative indices to differences in taxonomic richness and sample size (Barwell et al. 2015; Chao et al. 2006; Wolda 1981), although it is not without limitations, as discussed WebDescription. The Morisita-Horn index is a popular angular overlap measure used both in ecological and immunological literature. It quantifies overlap as cosine of an angle between two standardized population vectors. It ranges between zero (no overlap) and one (perfect overlap). MH tends to be over-sensitive to abundant species. WebApr 2, 2024 · The mean (per individual) SNP alpha-diversity ( q = 0) at the chromosome level for the 1000-Genomes Project: SNP (alpha) diversity at order q = 0 measures the number … sandy rock texture